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Use in pregnancy: There are no adequate data from the use of donepezil in pregnant women. Studies in animals have not shown teratogenic effect, but have shown peri- and postnatal toxicity (see Toxicology under Actions). The potential risk for humans is unknown. Aricept Evess should not be used during pregnancy unless clearly necessary.
Use in lactation: donepezil is excreted in the milk of rats. It is not known whether donepezil HCl is excreted in human breast milk and there are no studies in lactating women. Therefore, women on donepezil should not breastfeed.
